https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Refining the perfusion-diffusion mismatch hypothesis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:933 =20% was observed in 89% (Tmax) to 92% (TTP/FMT/MTT) of patients. Application of a +4s (relative to the contralateral hemisphere) PWI threshold reduced the frequency of positive mismatch volumes (TTP 73%/FMT 68%/Tmax 54%/MTT 43%). Mismatch was not significantly different when assessed with ADC maps. Mismatch volume, calculated with all parameters and thresholds, was not significantly correlated with DWI expansion. In contrast, reperfusion was correlated inversely with infarct growth (R=-0.51; P=0.009). Conclusions-: Deconvolution and application of PWI thresholds provide more conservative estimates of tissue at risk and decrease the frequency of mismatch accordingly. The precise definition may not be critical; however, because reperfusion alters tissue fate irrespective of mismatch.]]> Thu 01 Aug 2019 17:24:33 AEST ]]> Defining acute ischemic stroke tissue pathophysiology with whole brain CT perfusion https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19818 Sat 24 Mar 2018 07:56:57 AEDT ]]>